ELAVL4

Across TCGA patient cohorts, ELAVL4 mutation is significantly associated with the RNA expression of many other genes, with 2,864 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAVL4-associated genes across cancer lineages are PBK, SNRNP40, and CKAP2L. Each is linked with ELAVL4 in more than 4 cancer types. Because this analysis shows association rather than direction, both ELAVL4-to-partner and partner-to-ELAVL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PBK grouped by ELAVL4-low versus ELAVL4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL4→partner) and Y-score (partner→ELAVL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PBK →	+0.843	+2.081	<.001	.001	3	5
UCEC	SNRNP40 →	+0.611	+3.906	<.001	<.001	3	5
UCEC	CKAP2L →	+0.585	+2.346	.003	.003	3	5
UCEC	KCTD9 →	+0.561	+2.032	.001	.005	3	4
UCEC	C1QBP →	+0.511	+3.743	.001	<.001	3	4
UCEC	FOXRED1 →	+0.381	+3.743	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,864 associations by consensus.

PBK by ELAVL4 expression — UCEC

Explore this box plot interactively →