ELAVL4

Across TCGA cell cohorts, ELAVL4 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELAVL4-associated genes across cancer lineages are NUDT10, VAX1, and UTF1. Each is linked with ELAVL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELAVL4-to-partner and partner-to-ELAVL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUDT10 grouped by ELAVL4-low versus ELAVL4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL4→partner) and Y-score (partner→ELAVL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NUDT10 →	+0.363	+4.070	.001	<.001	3	1
LARGE_INTESTINE	VAX1 →	+0.648	+3.519	.001	.007	3	1
LARGE_INTESTINE	UTF1 →	+0.011	+3.217	.006	.006	3	1
LARGE_INTESTINE	SNTG2 →	+0.186	+4.052	<.001	<.001	3	1
LARGE_INTESTINE	C10orf53 →	+0.010	+4.047	.002	<.001	3	1
LARGE_INTESTINE	TRIM49B →	+0.232	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

NUDT10 by ELAVL4 expression — LARGE_INTESTINE

Explore this box plot interactively →