Across TCGA patient cohorts, ELAVL3 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAVL3-associated genes across cancer lineages are EGFR_pY1068, Notch1, and Chk2_pT68. Each is linked with ELAVL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELAVL3-to-partner and partner-to-ELAVL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL3→partner) and Y-score (partner→ELAVL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.218	-1.906	.030	.016	3	2
UCEC	Notch1 →	+0.117	+2.183	.039	.033	3	2
UCEC	Chk2_pT68 →	-0.152	-2.312	.042	.034	3	2
SKCM	Rad50 →	-0.283	-2.459	.042	.020	2	3
UCEC	14-3-3_beta →	-0.089	-2.973	.027	.035	3	1
UCEC	INPP4B →	-0.348	-3.459	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

ELAVL3 survival (RNA) · tumor vs normal (RNA) · all ELAVL3 data types