ELAVL2

Across TCGA patient cohorts, ELAVL2 mutation is significantly associated with the total protein of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAVL2-associated genes across cancer lineages are Cyclin-E2, FoxM1, and Notch1. Each is linked with ELAVL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ELAVL2-to-partner and partner-to-ELAVL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by ELAVL2-low versus ELAVL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL2→partner) and Y-score (partner→ELAVL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-E2 →	+0.106	+1.058	.033	.037	3	4
SKCM	FoxM1 →	+0.233	+3.000	.001	<.001	3	3
UCEC	Notch1 →	+0.168	+1.857	<.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.631	+3.087	<.001	<.001	3	3
LUSC	PKC-delta_pS664 →	-0.175	-2.972	.018	.036	3	2
UCEC	A-Raf_pS299 →	-0.116	-1.736	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

Cyclin-E2 by ELAVL2 expression — UCEC

Explore this box plot interactively →