ELAVL2

Across TCGA cell cohorts, ELAVL2 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ELAVL2-associated genes across cancer lineages are CHRND, OLIG3, and GPR139. Each is linked with ELAVL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELAVL2-to-partner and partner-to-ELAVL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHRND grouped by ELAVL2-low versus ELAVL2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL2→partner) and Y-score (partner→ELAVL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CHRND →	+0.030	+4.285	<.001	.003	3	2
LARGE_INTESTINE	OLIG3 →	+0.025	+3.247	<.001	.001	3	2
LUNG_SCLC	GPR139 →	+0.219	+2.635	.002	.007	3	2
UPPER_AERODIGESTIVE_TRACT	TSHB →	+0.348	+4.362	<.001	.001	3	2
UPPER_AERODIGESTIVE_TRACT	ZAN →	+0.028	+3.954	.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	PABPC1L2B →	+0.124	+4.321	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

CHRND by ELAVL2 expression — URINARY_TRACT

Explore this box plot interactively →