ELAVL1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ELAVL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ELAVL1 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ELAVL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ELAVL1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and COAD show a favorable association.

HNSC, PDAC, and COAD are the cancer types where ELAVL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSQuartileIV0.7361.000.00818view →
PDACDFSMedianAll0.8410.682.00413view →
COADDFSMedianAll1.0000.889.02412view →
UCECDFSMedianAll0.9331.000.01510view →
CCRCCOSMedianAll0.9490.851.0314view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ELAVL1–HNSC (OS)

Kaplan–Meier survival curve for ELAVL1 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration