ELAVL1

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ELAVL1 mass-spec protein differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of ELAVL1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ELAVL1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ELAVL1 is over-expressed in tumor.

COAD, HNSC, and LUAD are the cancer types where ELAVL1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELAVL1 mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADMaleIII,IV+0.401<.00110view →
HNSCMaleIV+0.188.0038view →
LUADMaleIII,IV+0.188<.0018view →
CCRCCMaleAll+0.131<.0018view →
LSCCMaleAll+0.348<.0017view →
OVAllAll+0.301.0282view →
PDACMaleAll+0.188.0341view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

ELAVL1–COAD

Tumor-vs-normal mass-spec protein box plot for ELAVL1 in COAD.

Open the COAD breakdown →

Exploration