ELAVL1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ELAVL1 mutation is significantly associated with the RNA expression of many other genes, with 3,564 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAVL1-associated genes across cancer lineages are IGHD1-20, MIR5584, and SH3GL1P2. Each is linked with ELAVL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELAVL1-to-partner and partner-to-ELAVL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD1-20 grouped by ELAVL1-low versus ELAVL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL1→partner) and Y-score (partner→ELAVL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECIGHD1-20 →+0.242+2.635<.001.00333
UCECMIR5584 →+0.093+2.700.002.00932
UCECSH3GL1P2 →+0.191+1.950.004.00232
UCECMIR4482 →+0.786+1.908<.001<.00132
HNSCOR4A15 →+0.038+5.936<.001.00132
HNSCRPS3AP33 →+0.105+4.197<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,564 associations by consensus.

IGHD1-20 by ELAVL1 expression — UCEC

Box plot of IGHD1-20 in ELAVL1-low vs ELAVL1-high samples in UCEC.

Explore this box plot interactively →

Exploration