ELAVL1

Across TCGA patient cohorts, ELAVL1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAVL1-associated genes across cancer lineages are Rad50, ERK2, and Annexin-1. Each is linked with ELAVL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELAVL1-to-partner and partner-to-ELAVL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rad50 grouped by ELAVL1-low versus ELAVL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL1→partner) and Y-score (partner→ELAVL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.171	-2.446	.025	.018	3	3
UCEC	ERK2 →	+0.155	+1.584	.010	.005	3	2
UCEC	Annexin-1 →	+0.451	+1.827	.006	.015	3	2
UCEC	TFRC →	+0.503	+1.584	.002	.005	3	2
UCEC	ASNS →	+0.349	+2.087	.002	.005	3	2
UCEC	C-Raf →	+0.131	+1.353	.003	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Rad50 by ELAVL1 expression — UCEC

Explore this box plot interactively →