ELAVL1

Across TCGA cell cohorts, ELAVL1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELAVL1-associated genes across cancer lineages are TEX43, ARSH, and TKTL2. Each is linked with ELAVL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELAVL1-to-partner and partner-to-ELAVL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX43 grouped by ELAVL1-low versus ELAVL1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL1→partner) and Y-score (partner→ELAVL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TEX43 →	+0.141	+5.969	<.001	.001	3	1
BLOOD_Leukemia	ARSH →	+0.012	+4.922	<.001	.009	3	1
LARGE_INTESTINE	TKTL2 →	+0.051	+4.509	<.001	<.001	3	1
LARGE_INTESTINE	ENPP6 →	+0.037	+3.115	<.001	.004	3	1
LARGE_INTESTINE	OR10A4 →	+0.051	+2.938	.001	.007	3	1
LARGE_INTESTINE	FAM153B →	+0.594	+3.618	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TEX43 by ELAVL1 expression — BLOOD_Leukemia

Explore this box plot interactively →