ELAPOR2

Across TCGA patient cohorts, ELAPOR2 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAPOR2-associated genes across cancer lineages are INPP4B, eIF4E, and Notch1. Each is linked with ELAPOR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELAPOR2-to-partner and partner-to-ELAPOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by ELAPOR2-low versus ELAPOR2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAPOR2→partner) and Y-score (partner→ELAPOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	INPP4B →	-0.161	-3.321	.032	.009	3	3
UCEC	eIF4E →	+0.155	+2.169	.014	.003	3	3
UCEC	Notch1 →	+0.155	+1.939	<.001	.002	3	3
UCEC	Caveolin-1 →	-0.455	-2.222	.038	.009	3	3
UCEC	4E-BP1 →	+0.262	+2.807	.001	.002	3	3
SKCM	MAPK_pT202_Y204 →	+0.712	+2.502	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

INPP4B by ELAPOR2 expression — SKCM

Explore this box plot interactively →