ELAPOR2

Across TCGA cell cohorts, ELAPOR2 mutation is significantly associated with the RNA expression of many other genes, with 1,364 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELAPOR2-associated genes across cancer lineages are NPHP4, TTPA, and DIRC1. Each is linked with ELAPOR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELAPOR2-to-partner and partner-to-ELAPOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPHP4 grouped by ELAPOR2-low versus ELAPOR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAPOR2→partner) and Y-score (partner→ELAPOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NPHP4 →	+0.556	+3.169	.005	.006	3	3
LUNG_NSCLC_LUAD	TTPA →	+0.856	+3.256	<.001	.009	3	2
LUNG_NSCLC_LUAD	DIRC1 →	+0.048	+2.887	.001	.009	3	2
SKIN	ZNF473 →	+0.465	+3.082	<.001	.007	3	2
SKIN	OR52A1 →	+0.032	+2.518	.001	.006	3	2
LARGE_INTESTINE	GINS1 →	+0.581	+2.265	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,364 associations by consensus.

NPHP4 by ELAPOR2 expression — LARGE_INTESTINE

Explore this box plot interactively →