ELAPOR1

Across TCGA patient cohorts, ELAPOR1 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAPOR1-associated genes across cancer lineages are ATM, A-Raf_pS299, and MEK1. Each is linked with ELAPOR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ELAPOR1-to-partner and partner-to-ELAPOR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by ELAPOR1-low versus ELAPOR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAPOR1→partner) and Y-score (partner→ELAPOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.453	-1.392	.002	.019	3	4
UCEC	A-Raf_pS299 →	-0.162	-4.000	<.001	<.001	3	2
UCEC	MEK1 →	+0.297	+2.263	.013	<.001	3	2
UCEC	Notch1 →	+0.130	+1.594	.004	.021	3	2
SKCM	PDK1_pS241 →	+0.164	+3.033	.018	.017	3	2
UCEC	Rab25 →	-0.431	-2.502	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

ATM by ELAPOR1 expression — UCEC

Explore this box plot interactively →