ELAPOR1

Across TCGA cell cohorts, ELAPOR1 mutation is significantly associated with the RNA expression of many other genes, with 681 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELAPOR1-associated genes across cancer lineages are OR56B1, RPS4Y2, and TEX26. Each is linked with ELAPOR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELAPOR1-to-partner and partner-to-ELAPOR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56B1 grouped by ELAPOR1-low versus ELAPOR1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAPOR1→partner) and Y-score (partner→ELAPOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR56B1 →	+0.083	+4.684	<.001	<.001	3	1
LUNG_SCLC	RPS4Y2 →	+0.343	+3.817	<.001	.004	3	1
BLOOD_Leukemia	TEX26 →	+0.035	+5.539	<.001	.003	3	1
BLOOD_Leukemia	ARMS2 →	+0.021	+4.922	.001	.009	3	1
LUNG_NSCLC_LUAD	MRGPRG →	+0.034	+4.544	<.001	.003	3	1
SKIN	OPN4 →	+0.054	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 681 associations by consensus.

OR56B1 by ELAPOR1 expression — LUNG_SCLC

Explore this box plot interactively →