ELAC2

Across TCGA patient cohorts, ELAC2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,826 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ELAC2-associated genes across cancer lineages are PRPSAP2, COX10, and C1QBP. Each is linked with ELAC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ELAC2-to-partner and partner-to-ELAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELAC2 versus PRPSAP2 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAC2→partner) and Y-score (partner→ELAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRPSAP2 →	+0.811	+0.496	<.001	<.001	3	9
LSCC	COX10 →	+0.555	+0.402	<.001	<.001	3	9
LSCC	C1QBP →	+0.805	+0.422	<.001	<.001	3	8
LSCC	RPA1 →	+0.737	+0.419	<.001	<.001	3	8
HNSC	YWHAE →	+0.651	+0.281	<.001	<.001	3	7
OV	TTC19 →	+0.474	+0.329	.004	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,826 associations by consensus.

ELAC2 vs PRPSAP2 — LSCC

Explore this scatter interactively →