ELAC2

Across TCGA cell cohorts, ELAC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,031 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELAC2-associated GO terms across cancer lineages are Mitochondrial DNA metabolic process, IMP biosynthetic process, and 'de novo' IMP biosynthetic process. Each is linked with ELAC2 in more than 16 cancer types. Because this analysis shows association rather than direction, both ELAC2-to-partner and partner-to-ELAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial DNA metabolic process grouped by ELAC2-low versus ELAC2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAC2→partner) and Y-score (partner→ELAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Mitochondrial DNA metabolic process →	+0.109	+0.743	.002	.001	2	17
URINARY_TRACT	IMP biosynthetic process →	+0.229	+1.041	<.001	<.001	3	16
LIVER	'de novo' IMP biosynthetic process →	+0.191	+1.038	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Telomere organization →	+0.078	+0.907	.002	<.001	3	16
SKIN	Ribosome biogenesis →	+0.092	+0.817	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Nucleobase biosynthetic process →	+0.143	+0.692	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,031 associations by consensus.

Mitochondrial DNA metabolic process by ELAC2 expression — LIVER

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