ELAC1

Across TCGA patient cohorts, ELAC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,374 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ELAC1-associated proteins across cancer lineages are SMAD4, ANP32E, and SMAD2. Each is linked with ELAC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ELAC1-to-partner and partner-to-ELAC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELAC1 versus SMAD4 in PDAC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAC1→partner) and Y-score (partner→ELAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SMAD4 →	+0.372	+0.441	<.001	<.001	3	9
BRCA	ANP32E →	+0.780	+0.668	<.001	<.001	3	6
COAD	SMAD2 →	+0.331	+0.340	<.001	<.001	3	6
OV	ELAC1_S146 →	+0.681	+0.451	<.001	<.001	3	6
OV	RPRD1A →	+0.563	+0.569	<.001	<.001	3	6
COAD	TXNL1 →	+0.423	+0.485	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,374 associations by consensus.

ELAC1 vs SMAD4 — PDAC

Explore this scatter interactively →