ELAC1

Across TCGA patient cohorts, ELAC1 mutation is significantly associated with the RNA expression of many other genes, with 961 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAC1-associated genes across cancer lineages are LINC01861, RN7SL870P, and YPEL5P2. Each is linked with ELAC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELAC1-to-partner and partner-to-ELAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01861 grouped by ELAC1-low versus ELAC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAC1→partner) and Y-score (partner→ELAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01861 →	+0.287	+5.771	<.001	.003	3	2
SKCM	RN7SL870P →	+0.149	+5.097	<.001	.008	3	2
UCEC	YPEL5P2 →	+0.281	+2.094	.004	.005	3	1
UCEC	LINC02084 →	+0.468	+3.491	<.001	.002	3	1
UCEC	RNA5SP414 →	+0.649	+2.139	<.001	.005	3	1
UCEC	C17orf98 →	+0.454	+3.019	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 961 associations by consensus.

LINC01861 by ELAC1 expression — SKCM

Explore this box plot interactively →