ELAC1

Across TCGA cell cohorts, ELAC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,849 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ELAC1-associated GO terms across cancer lineages are Left ventricular cardiac muscle tissue morphogenesis, Regulation of G0 to G1 transition, and Establishment of meiotic spindle orientation. Each is linked with ELAC1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ELAC1-to-partner and partner-to-ELAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Left ventricular cardiac muscle tissue morphogenesis grouped by ELAC1-low versus ELAC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAC1→partner) and Y-score (partner→ELAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Left ventricular cardiac muscle tissue morphogenesis →	+1.097	+1.150	.001	.002	3	13
BONE	Regulation of G0 to G1 transition →	+0.097	+0.978	.009	.004	2	10
BREAST	Establishment of meiotic spindle orientation →	+0.181	+1.432	<.001	<.001	3	9
LUNG_SCLC	DNA damage tolerance →	+0.088	+0.906	<.001	<.001	3	9
LARGE_INTESTINE	ESCRT complex disassembly →	+0.113	+0.675	<.001	<.001	3	8
LARGE_INTESTINE	ESCRT III complex disassembly →	+0.113	+0.675	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,849 associations by consensus.

Left ventricular cardiac muscle tissue morphogenesis by ELAC1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →