EIPR1

Across TCGA pan-cancer cohorts, EIPR1 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated EIPR1 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher EIPR1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated EIPR1 expression acts as an unfavorable survival marker.

ESCA, UCS, and LUSC are the cancer types where EIPR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.136	0.687	.001	30	view →
UCS	OS	Median	All	0.135	0.687	.009	24	view →
LUSC	OS	Median	All	0.179	0.777	<.001	24	view →
LIHC	DFS	Median	All	0.081	0.527	.012	15	view →
KIRC	OS	Median	All	0.167	0.655	.038	12	view →
LUAD	OS	Median	All	0.266	0.790	.007	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

EIPR1–ESCA (OS)

Open the ESCA breakdown →