EIPR1

Across TCGA patient cohorts, EIPR1 mutation is significantly associated with the RNA expression of many other genes, with 809 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIPR1-associated genes across cancer lineages are RNA5SP52, RPL23AP4, and HDAC9-AS1. Each is linked with EIPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EIPR1-to-partner and partner-to-EIPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP52 grouped by EIPR1-low versus EIPR1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIPR1→partner) and Y-score (partner→EIPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNA5SP52 →	+0.442	+6.257	<.001	.001	3	2
READ	RPL23AP4 →	+0.141	+5.039	<.001	.008	3	2
READ	HDAC9-AS1 →	+0.220	+7.276	<.001	<.001	3	2
READ	RPS7P2 →	+0.245	+5.925	<.001	.002	3	2
UCEC	RPS29P32 →	+0.629	+2.751	<.001	.002	3	2
UCEC	SNORD90 →	+0.346	+2.407	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 809 associations by consensus.

RNA5SP52 by EIPR1 expression — READ

Explore this box plot interactively →