EIPR1

Across TCGA patient cohorts, EIPR1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIPR1-associated genes across cancer lineages are GAPDH, JNK_pT183_Y185, and PCNA. Each is linked with EIPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EIPR1-to-partner and partner-to-EIPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by EIPR1-low versus EIPR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIPR1→partner) and Y-score (partner→EIPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.650	+3.321	.020	.010	2	2
UCEC	JNK_pT183_Y185 →	-0.232	-3.308	.008	.010	3	1
UCEC	PCNA →	+0.325	+3.169	.004	.019	3	1
UCEC	Rb_pS807_S811 →	+0.500	+3.000	.018	.036	3	1
UCEC	STAT3_pY705 →	-0.375	-2.999	.006	.035	3	1
UCEC	MSH2 →	-0.493	-2.990	<.001	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

GAPDH by EIPR1 expression — UCEC

Explore this box plot interactively →