EIPR1

Across TCGA cell cohorts, EIPR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,406 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible EIPR1-associated GO terms across cancer lineages are 'de novo' pyrimidine nucleobase biosynthetic process, DNA replication, removal of RNA primer, and DNA-templated DNA replication. Each is linked with EIPR1 in more than 10 cancer types. Because this analysis shows association rather than direction, both EIPR1-to-partner and partner-to-EIPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' pyrimidine nucleobase biosynthetic process grouped by EIPR1-low versus EIPR1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIPR1→partner) and Y-score (partner→EIPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	'de novo' pyrimidine nucleobase biosynthetic process →	+0.148	+0.496	.003	.004	3	11
UPPER_AERODIGESTIVE_TRACT	DNA replication, removal of RNA primer →	+0.186	+0.928	<.001	.001	2	11
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.081	+0.664	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation involved in DNA replication →	+0.102	+0.631	.001	<.001	3	9
BLOOD_Lymphoma	Meiotic sister chromatid cohesion, centromeric →	+0.100	+0.773	.004	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.160	+0.834	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,406 associations by consensus.

'de novo' pyrimidine nucleobase biosynthetic process by EIPR1 expression — BONE

Explore this box plot interactively →