EIPR1-IT1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, EIPR1-IT1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of EIPR1-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where EIPR1-IT1 RNA is repressed in tumor relative to normal tissue. In most cancer types EIPR1-IT1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and STAD are the cancer types where EIPR1-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIPR1-IT1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAMaleIV−2.746<.00111view →
KIRCMaleII,III,IV−0.826<.0019view →
STADAllIII,IV+0.423<.0019view →
LUADAllAll+0.551<.0018view →
COADAllAll+0.241<.0017view →
UCECAllAll+0.886<.0016view →
BLCAAllAll+0.644.0036view →
BRCAAllAll+0.492<.0016view →
LUSCFemaleAll+1.014<.0015view →
KICHMaleAll−0.762.0202view →
READFemaleAll+0.564.0172view →
KIRPAllAll−0.390.0032view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

Exploration