EIF6

Across TCGA patient cohorts, EIF6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,387 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF6-associated genes across cancer lineages are UQCC1, NFS1, and RAE1. Each is linked with EIF6 in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF6-to-partner and partner-to-EIF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF6 versus UQCC1 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF6→partner) and Y-score (partner→EIF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UQCC1 →	+0.557	+0.357	<.001	.003	2	8
COAD	NFS1 →	+0.518	+0.407	<.001	<.001	3	7
COAD	RAE1 →	+0.635	+0.270	<.001	<.001	3	6
UCEC	AHCY →	+0.902	+0.230	.006	.004	2	7
UCEC	EIF2S2 →	+0.601	+0.269	.005	<.001	2	7
COAD	ZFAS1 →	+0.700	+0.407	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,387 associations by consensus.

EIF6 vs UQCC1 — OV

Explore this scatter interactively →