EIF5B

Across TCGA patient cohorts, EIF5B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,286 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF5B-associated proteins across cancer lineages are C1orf35, TXNDC9, and RANBP2. Each is linked with EIF5B in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF5B-to-partner and partner-to-EIF5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF5B versus C1orf35 in GBM, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5B→partner) and Y-score (partner→EIF5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	C1orf35 →	+0.375	+0.263	.001	.002	3	6
PDAC	TXNDC9 →	+0.330	+0.384	<.001	<.001	3	6
GBM	RANBP2 →	+0.207	+0.265	<.001	.001	3	5
UCEC	SLC4A1AP →	+0.346	+0.445	<.001	<.001	3	5
GBM	SMARCA5 →	+0.334	+0.330	<.001	<.001	3	5
LSCC	IMP4 →	+0.242	+0.448	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,286 associations by consensus.

EIF5B vs C1orf35 — GBM

Explore this scatter interactively →