EIF5AP4

Across TCGA pan-cancer cohorts, EIF5AP4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated EIF5AP4 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher EIF5AP4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EIF5AP4 expression acts as an unfavorable survival marker, although some lineages such as UCS and READ show a favorable association.

ACC, LUAD, and UVM are the cancer types where EIF5AP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.289	0.779	<.001	82	view →
LUAD	OS	Tertile	II,III,IV	0.608	0.793	<.001	74	view →
UVM	OS	Median	All	0.443	0.737	.002	52	view →
CHOL	DFS	Tertile	All	0.124	0.523	.001	33	view →
UCS	OS	Median	IV	0.732	0.224	.018	24	view →
READ	DFS	Quartile	II,III,IV	0.709	0.215	.004	16	view →
LUSC	DFS	Median	II,III,IV	0.449	0.279	.005	15	view →
LIHC	OS	Median	II,III,IV	0.521	0.691	.023	14	view →
UCEC	DFS	Median	II,III,IV	0.664	0.790	.018	12	view →
KIRP	DFS	Quartile	All	0.742	1.000	.005	9	view →
THCA	DFS	Tertile	II,III,IV	0.576	0.910	.004	8	view →
HNSC	DFS	Tertile	II,III,IV	0.637	0.763	.025	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

EIF5AP4–ACC (DFS)

Open the ACC breakdown →