EIF5A

Across TCGA cell cohorts, EIF5A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,560 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF5A-associated GO terms across cancer lineages are RNA folding, Telomere assembly, and rRNA processing. Each is linked with EIF5A in more than 17 cancer types. Because this analysis shows association rather than direction, both EIF5A-to-partner and partner-to-EIF5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA folding grouped by EIF5A-low versus EIF5A-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5A→partner) and Y-score (partner→EIF5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	RNA folding →	+0.183	+1.348	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Telomere assembly →	+0.152	+0.894	<.001	<.001	3	17
LUNG_SCLC	rRNA processing →	+0.116	+0.999	<.001	<.001	3	16
LUNG_SCLC	Ribosome biogenesis →	+0.101	+0.993	<.001	<.001	3	16
LUNG_SCLC	rRNA metabolic process →	+0.112	+1.043	<.001	<.001	3	15
BREAST	Thymidine biosynthetic process →	+0.160	+1.149	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,560 associations by consensus.

RNA folding by EIF5A expression — BLOOD_Myeloma

Explore this box plot interactively →