EIF5

Across TCGA patient cohorts, EIF5 protein abundance is significantly associated with the RNA expression of many other genes, with 9,053 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF5-associated genes across cancer lineages are CINP, COA8, and RCOR1. Each is linked with EIF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF5-to-partner and partner-to-EIF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF5 versus CINP in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5→partner) and Y-score (partner→EIF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CINP →	+0.481	+0.324	<.001	<.001	3	7
OV	COA8 →	+0.393	+0.276	<.001	<.001	3	6
HNSC	RCOR1 →	+0.755	+0.358	<.001	<.001	3	6
LSCC	TIMM9 →	+0.523	+0.312	<.001	<.001	3	5
LSCC	CDCA4 →	+0.785	+0.290	<.001	<.001	3	5
LSCC	TRMT61A →	+0.669	+0.312	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,053 associations by consensus.

EIF5 vs CINP — LSCC

Explore this scatter interactively →