EIF5

Across TCGA cell cohorts, EIF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,823 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EIF5-associated GO terms across cancer lineages are Positive regulation of cell cycle, Transcription elongation by RNA polymerase II, and RNA export from nucleus. Each is linked with EIF5 in more than 14 cancer types. Because this analysis shows association rather than direction, both EIF5-to-partner and partner-to-EIF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle grouped by EIF5-low versus EIF5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5→partner) and Y-score (partner→EIF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of cell cycle →	+0.074	+1.017	<.001	<.001	3	15
BREAST	Transcription elongation by RNA polymerase II →	+0.085	+1.076	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.115	+0.872	.001	.006	3	14
BREAST	Nucleic acid transport →	+0.086	+0.782	<.001	.004	3	14
BREAST	RNA transport →	+0.086	+0.782	<.001	.004	3	14
LARGE_INTESTINE	RISC complex assembly →	+0.121	+0.985	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,823 associations by consensus.

Positive regulation of cell cycle by EIF5 expression — BREAST

Explore this box plot interactively →