EIF4G3

Across TCGA patient cohorts, EIF4G3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,945 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF4G3-associated proteins across cancer lineages are EIF4G3_S1409, TUBB6, and UBE4B. Each is linked with EIF4G3 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF4G3-to-partner and partner-to-EIF4G3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4G3 versus EIF4G3_S1409 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4G3→partner) and Y-score (partner→EIF4G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EIF4G3_S1409 →	+0.691	+0.691	.001	.001	3	7
OV	TUBB6 →	+0.556	+1.031	<.001	<.001	3	4
LSCC	UBE4B →	+0.329	+0.452	<.001	<.001	3	4
LSCC	PSME2 →	-0.323	-0.296	.001	.006	3	4
GBM	PUM1 →	+0.208	+0.391	.001	.001	3	4
OV	SEPTIN11 →	+0.381	+0.826	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,945 associations by consensus.

EIF4G3 vs EIF4G3_S1409 — OV

Explore this scatter interactively →