EIF4G2

Across TCGA patient cohorts, EIF4G2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,611 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EIF4G2-associated proteins across cancer lineages are CAPRIN1, CELF1, and COQ9. Each is linked with EIF4G2 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF4G2-to-partner and partner-to-EIF4G2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4G2 versus CAPRIN1 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4G2→partner) and Y-score (partner→EIF4G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CAPRIN1 →	+0.298	+0.404	.001	<.001	3	7
LSCC	CELF1 →	+0.234	+0.319	.001	.003	3	6
OV	COQ9 →	-0.412	-0.370	.002	.007	3	5
GBM	DBN1 →	+0.416	+0.356	<.001	<.001	3	5
HNSC	IPO7 →	+0.248	+0.520	<.001	<.001	3	5
UCEC	RRM1 →	+0.602	+0.545	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,611 associations by consensus.

EIF4G2 vs CAPRIN1 — GBM

Explore this scatter interactively →