EIF4G2

Across TCGA patient cohorts, EIF4G2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,206 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF4G2-associated genes across cancer lineages are PSMD13, CDC20, and TUBA1C. Each is linked with EIF4G2 in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF4G2-to-partner and partner-to-EIF4G2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4G2 versus PSMD13 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4G2→partner) and Y-score (partner→EIF4G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PSMD13 →	+0.758	+0.220	<.001	<.001	3	8
BRCA	CDC20 →	+1.040	+0.202	<.001	<.001	3	7
HNSC	TUBA1C →	+0.806	+0.315	<.001	<.001	3	6
HNSC	RIC8A →	+0.633	+0.275	<.001	<.001	3	6
UCEC	MEX3A →	+1.307	+0.205	<.001	<.001	3	6
GBM	CENPA →	+0.799	+0.130	<.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,206 associations by consensus.

EIF4G2 vs PSMD13 — HNSC

Explore this scatter interactively →