EIF4G1

Across TCGA patient cohorts, EIF4G1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,567 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF4G1-associated proteins across cancer lineages are ABCF3, FXR1, and GMPS. Each is linked with EIF4G1 in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF4G1-to-partner and partner-to-EIF4G1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4G1 versus ABCF3 in LSCC, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4G1→partner) and Y-score (partner→EIF4G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABCF3 →	+0.433	+0.845	<.001	<.001	3	8
LSCC	FXR1 →	+0.518	+0.838	<.001	<.001	3	7
LSCC	GMPS →	+0.479	+0.721	<.001	<.001	3	7
LSCC	POLR2H →	+0.393	+0.638	<.001	<.001	3	6
PDAC	MPRIP_S301 →	-0.747	-0.377	<.001	<.001	3	5
LSCC	MSH2 →	+0.421	+0.773	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,567 associations by consensus.

EIF4G1 vs ABCF3 — LSCC

Explore this scatter interactively →