EIF4G1

Across TCGA patient cohorts, EIF4G1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,818 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF4G1-associated genes across cancer lineages are ZNF540, PSMD2, and DNAJB11. Each is linked with EIF4G1 in more than 9 cancer types. Because this analysis shows association rather than direction, both EIF4G1-to-partner and partner-to-EIF4G1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4G1 versus ZNF540 in BRCA, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4G1→partner) and Y-score (partner→EIF4G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF540 →	-0.848	-0.222	<.001	<.001	3	10
LSCC	PSMD2 →	+0.987	+0.381	<.001	<.001	3	10
LSCC	DNAJB11 →	+0.736	+0.292	<.001	<.001	3	10
BRCA	TNS2 →	-0.923	-0.218	<.001	<.001	3	9
LSCC	MRPL47 →	+0.930	+0.375	<.001	<.001	3	9
UCEC	N4BP2L1 →	-0.635	-0.256	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,818 associations by consensus.

EIF4G1 vs ZNF540 — BRCA

Explore this scatter interactively →