EIF4EP4

Across TCGA patient cohorts, EIF4EP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,961 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EIF4EP4-associated GO terms across cancer lineages are Positive regulation of nervous system development, Positive regulation of microtubule polymerization or depolymerization, and Regulation of protein localization to nucleus. Each is linked with EIF4EP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF4EP4-to-partner and partner-to-EIF4EP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of nervous system development grouped by EIF4EP4-low versus EIF4EP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EP4→partner) and Y-score (partner→EIF4EP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of nervous system development →	+0.056	+0.067	<.001	<.001	3	5
STAD	Positive regulation of microtubule polymerization or depolymerization →	+0.081	+0.059	<.001	.001	3	5
STAD	Regulation of protein localization to nucleus →	+0.110	+0.076	<.001	.001	3	4
STAD	Regulation of telomerase activity →	+0.091	+0.078	<.001	.002	3	4
STAD	Negative regulation of small molecule metabolic process →	+0.065	+0.075	<.001	.002	3	4
STAD	Nucleoside phosphate biosynthetic process →	+0.097	+0.090	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,961 associations by consensus.

Positive regulation of nervous system development by EIF4EP4 expression — STAD

Explore this box plot interactively →