EIF4EP1

Across TCGA pan-cancer cohorts, EIF4EP1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated EIF4EP1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher EIF4EP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF4EP1 expression acts as an unfavorable survival marker, although some lineages such as ACC and HNSC show a favorable association.

THCA, CESC, and ACC are the cancer types where EIF4EP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.795	1.000	.003	52	view →
CESC	DFS	Quartile	All	0.611	0.798	.004	48	view →
ACC	OS	Quartile	II,III,IV	0.866	0.294	.005	33	view →
LGG	DFS	Tertile	All	0.330	0.514	<.001	29	view →
HNSC	DFS	Quartile	II,III,IV	0.825	0.578	.007	29	view →
READ	OS	Median	II,III,IV	0.852	0.397	.004	26	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LUAD	DFS	Tertile	IV	0.192	0.876	.011	24	view →
SKCM	OS	Quartile	III,IV	0.565	0.175	.002	20	view →
OV	OS	Tertile	IV	0.585	0.928	<.001	20	view →
KIRC	DFS	Median	IV	0.233	0.420	.016	16	view →
BRCA	DFS	Quartile	III,IV	0.852	0.679	.006	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

EIF4EP1–THCA (OS)

Open the THCA breakdown →