EIF4ENIF1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EIF4ENIF1 mutation is significantly associated with the RNA expression of many other genes, with 3,631 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF4ENIF1-associated genes across cancer lineages are TRGJP1, ADNP2, and ZWINT. Each is linked with EIF4ENIF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EIF4ENIF1-to-partner and partner-to-EIF4ENIF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4ENIF1→partner) and Y-score (partner→EIF4ENIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCTRGJP1 →+0.755+5.108<.001.00833
UCECADNP2 →+0.513+2.040<.001.00533
UCECZWINT →+0.741+3.247<.001<.00133
UCECXPO7 →+0.408+2.162.001.00233
UCECBUB3 →+0.465+3.075<.001<.00133
UCECMAP6D1 →+0.391+2.247.005.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,631 associations by consensus.

Exploration