Across TCGA cell cohorts, EIF4ENIF1 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EIF4ENIF1-associated genes across cancer lineages are DPPA5, OR5V1, and APCS. Each is linked with EIF4ENIF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF4ENIF1-to-partner and partner-to-EIF4ENIF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4ENIF1→partner) and Y-score (partner→EIF4ENIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DPPA5 →	+0.050	+4.981	<.001	.008	3	2
SKIN	OR5V1 →	+0.023	+4.977	<.001	.007	3	2
LUNG_SCLC	APCS →	+0.056	+5.643	<.001	.002	3	1
LUNG_SCLC	MRGPRX1 →	+0.216	+5.643	<.001	.002	3	1
LUNG_SCLC	MAGEB5 →	+0.020	+5.643	<.001	.002	3	1
LUNG_NSCLC_LUAD	LYZL1 →	+0.020	+4.887	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

EIF4ENIF1 survival (RNA) · tumor vs normal (RNA) · all EIF4ENIF1 data types