EIF4EBP2

Across TCGA patient cohorts, EIF4EBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,304 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EIF4EBP2-associated genes across cancer lineages are BIRC5, WAPL, and CCDC186. Each is linked with EIF4EBP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF4EBP2-to-partner and partner-to-EIF4EBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4EBP2 versus BIRC5 in LUAD, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EBP2→partner) and Y-score (partner→EIF4EBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BIRC5 →	-0.936	-0.192	<.001	<.001	3	5
BRCA	WAPL →	+0.579	+0.363	<.001	<.001	3	5
BRCA	CCDC186 →	+0.555	+0.303	.008	<.001	3	5
OV	FOXM1 →	-0.992	-0.240	.003	.007	3	4
LUAD	CDC20 →	-1.022	-0.198	<.001	<.001	3	4
LUAD	HJURP →	-1.060	-0.222	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,304 associations by consensus.

EIF4EBP2 vs BIRC5 — LUAD

Explore this scatter interactively →