EIF4EBP2

Across TCGA cell cohorts, EIF4EBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,310 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EIF4EBP2-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Regulation of G0 to G1 transition, and Positive regulation of mitochondrial ATP synthesis coupled electron transport. Each is linked with EIF4EBP2 in more than 13 cancer types. Because this analysis shows association rather than direction, both EIF4EBP2-to-partner and partner-to-EIF4EBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by EIF4EBP2-low versus EIF4EBP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EBP2→partner) and Y-score (partner→EIF4EBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.086	+1.009	.001	.002	3	14
BLOOD_Lymphoma	Regulation of G0 to G1 transition →	+0.102	+0.783	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.134	+1.090	<.001	.001	3	13
SOFT_TISSUE	Regulation of nucleotide-excision repair →	+0.106	+0.769	<.001	<.001	3	13
BONE	Regulation of double-strand break repair via homologous recombination →	+0.138	+0.985	<.001	<.001	3	13
BONE	Regulation of coagulation →	-0.155	-0.698	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,310 associations by consensus.

Positive regulation of double-strand break repair by EIF4EBP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →