Across TCGA patient cohorts, EIF4EBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,679 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF4EBP1-associated genes across cancer lineages are ADAM9, BRF2, and ASH2L. Each is linked with EIF4EBP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF4EBP1-to-partner and partner-to-EIF4EBP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EBP1→partner) and Y-score (partner→EIF4EBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADAM9 →	+1.029	+0.371	<.001	<.001	3	5
UCEC	BRF2 →	+1.243	+0.286	<.001	<.001	3	4
LSCC	ASH2L →	+0.760	+0.285	<.001	<.001	3	4
LSCC	PLPBP →	+0.741	+0.296	<.001	<.001	3	4
UCEC	LSM1 →	+0.976	+0.335	<.001	<.001	3	4
HNSC	BAG4 →	+0.924	+0.279	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,679 associations by consensus.

Exploration

EIF4EBP1 survival (RNA) · tumor vs normal (RNA) · all EIF4EBP1 data types