EIF4E3

Across TCGA patient cohorts, EIF4E3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,404 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EIF4E3-associated proteins across cancer lineages are PPP1R12B, DDAH1, and METTL1. Each is linked with EIF4E3 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF4E3-to-partner and partner-to-EIF4E3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4E3 versus PPP1R12B in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4E3→partner) and Y-score (partner→EIF4E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP1R12B →	+0.621	+0.770	<.001	<.001	3	6
BRCA	DDAH1 →	+0.555	+0.574	<.001	<.001	3	6
LUAD	METTL1 →	-0.349	-0.606	<.001	<.001	3	6
LSCC	NSUN4 →	-0.293	-0.538	<.001	<.001	3	5
HNSC	PRMT3 →	-0.522	-0.702	<.001	<.001	3	5
BRCA	RUFY1 →	+0.300	+0.762	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,404 associations by consensus.

EIF4E3 vs PPP1R12B — BRCA

Explore this scatter interactively →