EIF4E3

Across TCGA patient cohorts, EIF4E3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,871 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF4E3-associated genes across cancer lineages are RAI2, ABCD2, and LINC02884. Each is linked with EIF4E3 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF4E3-to-partner and partner-to-EIF4E3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4E3 versus RAI2 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4E3→partner) and Y-score (partner→EIF4E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAI2 →	+1.390	+0.345	.001	.002	3	6
LSCC	ABCD2 →	+0.652	+0.284	<.001	<.001	3	6
PDAC	LINC02884 →	+0.645	+0.197	<.001	.001	3	6
LSCC	CPED1 →	+0.899	+0.384	<.001	<.001	3	5
GBM	ASPA →	+1.199	+0.395	<.001	<.001	3	5
UCEC	SGCA →	+0.803	+0.323	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,871 associations by consensus.

EIF4E3 vs RAI2 — BRCA

Explore this scatter interactively →