Across TCGA pan-cancer cohorts, EIF4BP6 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of EIF4BP6’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where EIF4BP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EIF4BP6 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.
LIHC, KIRC, and BRCA are the cancer types where EIF4BP6 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF4BP6 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.