EIF4B

Across TCGA cell cohorts, EIF4B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,300 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EIF4B-associated GO terms across cancer lineages are Oocyte growth, Extracellular matrix organization, and CAMKK-AMPK signaling cascade. Each is linked with EIF4B in more than 13 cancer types. Because this analysis shows association rather than direction, both EIF4B-to-partner and partner-to-EIF4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by EIF4B-low versus EIF4B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4B→partner) and Y-score (partner→EIF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Oocyte growth →	+0.186	+0.968	<.001	<.001	3	14
BONE	Extracellular matrix organization →	-0.230	-1.039	<.001	<.001	3	12
STOMACH	CAMKK-AMPK signaling cascade →	+0.134	+0.859	.007	.009	1	14
BONE	Extracellular structure organization →	-0.230	-1.039	<.001	<.001	3	11
LARGE_INTESTINE	RNA destabilization →	+0.066	+1.150	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	mRNA destabilization →	+0.067	+0.899	.004	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,300 associations by consensus.

Oocyte growth by EIF4B expression — PANCREAS

Explore this box plot interactively →