EIF4A3P1

Across TCGA pan-cancer cohorts, EIF4A3P1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated EIF4A3P1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher EIF4A3P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF4A3P1 expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

BLCA, KICH, and TGCT are the cancer types where EIF4A3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.123	0.693	<.001	54	view →
KICH	DFS	Tertile	All	0.102	0.848	.004	39	view →
TGCT	DFS	Tertile	II,III,IV	0.051	0.955	<.001	36	view →
READ	OS	Tertile	III,IV	0.334	0.752	.024	36	view →
PCPG	DFS	Tertile	All	0.086	0.768	<.001	18	view →
LIHC	DFS	Tertile	All	0.161	0.555	.032	12	view →
STAD	DFS	Tertile	III,IV	0.726	0.552	.024	9	view →
GBM	OS	Tertile	All	0.155	0.427	.001	9	view →
THCA	DFS	Tertile	II,III,IV	0.151	0.678	.049	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

EIF4A3P1–BLCA (OS)

Open the BLCA breakdown →