EIF4A3

Across TCGA patient cohorts, EIF4A3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,192 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF4A3-associated proteins across cancer lineages are KPNA2, MCM4, and ATAD2. Each is linked with EIF4A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF4A3-to-partner and partner-to-EIF4A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4A3 versus KPNA2 in LUAD, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A3→partner) and Y-score (partner→EIF4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KPNA2 →	+0.552	+0.469	<.001	<.001	3	7
GBM	MCM4 →	+0.730	+0.283	<.001	<.001	3	7
BRCA	ATAD2 →	+0.486	+0.407	<.001	.001	3	7
UCEC	TK1 →	+0.678	+0.854	<.001	<.001	3	7
LSCC	USP36 →	+0.424	+0.522	<.001	<.001	3	7
LSCC	NLE1 →	+0.454	+0.506	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,192 associations by consensus.

EIF4A3 vs KPNA2 — LUAD

Explore this scatter interactively →