EIF4A3

Across TCGA patient cohorts, EIF4A3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,440 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF4A3-associated genes across cancer lineages are NUP85, NOL11, and CCDC150. Each is linked with EIF4A3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF4A3-to-partner and partner-to-EIF4A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4A3 versus NUP85 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A3→partner) and Y-score (partner→EIF4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUP85 →	+0.774	+0.251	<.001	<.001	3	8
LSCC	NOL11 →	+0.727	+0.322	<.001	<.001	3	8
UCEC	CCDC150 →	+0.986	+0.282	<.001	<.001	3	8
HNSC	SRSF2 →	+0.542	+0.168	<.001	<.001	3	8
UCEC	POLE →	+0.892	+0.199	<.001	.005	3	8
BRCA	HASPIN →	+0.718	+0.177	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,440 associations by consensus.

EIF4A3 vs NUP85 — BRCA

Explore this scatter interactively →