EIF4A2P5

Across TCGA pan-cancer cohorts, EIF4A2P5 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated EIF4A2P5 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher EIF4A2P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF4A2P5 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

LUAD, ESCA, and PCPG are the cancer types where EIF4A2P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	IV	0.153	0.714	.012	45	view →
ESCA	DFS	Tertile	All	0.681	0.328	.017	36	view →
PCPG	DFS	Tertile	All	0.159	0.830	<.001	27	view →
READ	OS	Tertile	III,IV	0.644	0.932	<.001	24	view →
BLCA	OS	Tertile	III,IV	0.235	0.591	.020	18	view →
PAAD	DFS	Tertile	All	0.781	0.261	.028	6	view →
HNSC	OS	Tertile	III,IV	0.376	0.685	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

EIF4A2P5–LUAD (OS)

Open the LUAD breakdown →